Download PDF
Synthesis 1996; 1996(3): 403-406
DOI: 10.1055/s-1996-4214
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Simple Route to 3-Substituted 2-Cyano Allylic Alcohols

Mouna Aiai, Michèle Baudy-Floc’h, Albert Robert, Philippe Le Grel*
  • *Laboratoire de Chimie Structurale, URA CNRS 704, Université de Rennes I, Campus de Beaulieu, F-35042 Rennes Cédex, France, Fax +33(99)286739
Further Information

Publication History

Publication Date:
31 December 2000 (online)

 PDF Download  Permissions and Reprints All articles of this category
Preview

The first original and simple route to 3-substituted 2-cyano allylic alcohols with very good yields is described. The epoxide function in the key step acts as a protecting group during the synthesis of these allylic alcohols.

2-cyano allylic alcohols - bromohydrins - stereoselective ring opening - reduction - epoxide function as protecting group